Ryser et al., Mol Immunol 2008
:
S1P(1) overexpression resulted in reduced CXCR4 surface expression levels and strong inhibition of SDF-1 dependent ERK1/2 phosphorylation and Ca ( 2+ ) flux
Möhle et al., Ann N Y Acad Sci 2012
:
Stimulation of S1P1 or C3aR has been shown to activate CXCR4 in HPCs that may sensitize CXCR4 dependent stem cell homing