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NOS1 — S100A12
Text-mined interactions from Literome
Akiba et al., Am J Physiol Gastrointest Liver Physiol 2001
:
Antagonism of vanilloid and
CGRP receptors,
inhibition of
nitric oxide synthase , and sensory deafferentation delayed gel thickening, suggesting that the capsaicin pathway mediated the initial burst of mucus secretion that thickened the gel
Wang et al., Am J Physiol Heart Circ Physiol 2004
(Hyperplasia) :
Furthermore,
CGRP gene transfer
increased inducible
nitric oxide synthase and p53 but decreased PCNA and Bcl-2 protein levels in balloon injured rat aorta
Harada et al., Thromb Haemost 2005
(Disease Models, Animal...) :
In this process,
CGRP induced
activation of both endothelial
nitric oxide synthase and cyclooxygenase-1 might be critically involved
E et al., J Invest Dermatol 2006
:
Experimental evidence suggested that
CGRP stimulated both
constitutive NOS activity and generation of NO via nitrosothiol degradation within the first hour
Li et al., Zhongguo Ying Yong Sheng Li Xue Za Zhi 2004
(Pain) :
[
Effect of CGRP receptor antagonist
CGRP8-37 on nociceptive response,
NOS expression and NO content in the dorsal horn of spinal cord during formalin induced inflammatory pain in rats ] ... To study the
effect of CGRP receptor antagonist
CGRP8-37 on nociceptive response and expression of
nitric oxide synthase (NOS) and content of nitric oxide ( NO ) in the dorsal horn of the spinal cord of rats during formalin induced inflammatory pain ... The activation of
CGRP receptors
enhances NOS expression and NO production in the dorsal horn of the spinal cord during formalin induced inflammatory pain
Wang et al., Exp Neurol 2013
:
Moreover, AM-induced increase of
CGRP was
inhibited by the
nNOS inhibitors L-NAME and 7-nitroindazole in cultured ganglion explants
Yoshimoto et al., Br J Pharmacol 1998
:
8. These results suggest that in the rat aorta, adrenomedullin and
alpha-CGRP increase the endothelial [ Ca2+ ] i, activate
nitric oxide synthase and release nitric oxide, without a direct inhibitory action on smooth muscle