Gene interactions and pathways from curated databases and text-mining

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PRKAR2A — RUNX2

Text-mined interactions from Literome

Franceschi et al., Connect Tissue Res 2003 : Interactions with Runx2 are complex involving both binding of distinct components such as AP-1 factors and Smads to separate sites on DNA, direct interactions between Runx2 and AP-1/Smad factors and MAPK or PKA dependent Runx2 phosphorylation
Chen et al., Kidney Int 2006 (Uremia) : The results demonstrate that the cyclic AMP ( cAMP ) /protein kinase A (PKA) , but not protein kinase C, signaling pathway is involved in uremic serum induced RUNX2 expression and ALP activity in BVSMCs
Satoh et al., Hypertens Res 1995 : We reported a novel intracellular mechanism of renal Na-K-ATPase regulation by dopamine ( DA ) in the rat cortical collecting duct (CCD) , which involves stimulation of protein kinase A (PKA) and phospholipase A2 (PLA2)