Gene interactions and pathways from curated databases and text-mining

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AKT1 — RRAS

Text-mined interactions from Literome

Marte et al., Curr Biol 1997 (Cell Transformation, Neoplastic) : In co-transfection assays, the serine/threonine protein kinase PKB ( or Akt ) is effectively stimulated by R-Ras , Ras, mutants of Ras that activate PI 3-kinase but not other effectors, and activated forms of PI 3-kinase ... Ras and R-Ras stimulate PKB/Akt through a non-autocrine mechanism that involves PI 3-kinase ... Ras and R-Ras stimulate PKB/Akt through a non-autocrine mechanism that involves PI 3-kinase
Suzuki et al., FEBS Lett 1998 : In contrast, Akt was activated strongly by R-Ras , but weakly by IGF-1