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AKT1 — RRAS
Text-mined interactions from Literome
Marte et al., Curr Biol 1997
(Cell Transformation, Neoplastic) :
In co-transfection assays, the serine/threonine protein kinase
PKB ( or Akt ) is effectively
stimulated by
R-Ras , Ras, mutants of Ras that activate PI 3-kinase but not other effectors, and activated forms of PI 3-kinase ... Ras and
R-Ras stimulate
PKB/Akt through a non-autocrine mechanism that involves PI 3-kinase ... Ras and
R-Ras stimulate
PKB/Akt through a non-autocrine mechanism that involves PI 3-kinase
Suzuki et al., FEBS Lett 1998
:
In contrast,
Akt was
activated strongly by
R-Ras , but weakly by IGF-1