Gene interactions and pathways from curated databases and text-mining

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IGF2 — RPTOR

Text-mined interactions from Literome

Martin et al., Biol Reprod 2003 : The resultant mTOR signaling could trigger polyamine, insulin-like growth factor II , and nitric oxide production in blastocysts and the increased cell motility sometimes associated with synthesis of these bioactive molecules
Burgos et al., Domest Anim Endocrinol 2010 : In addition, IGF-1 stimulated mTORC1 kinase activity toward 4E-BP1 in vitro
Melnik et al., Hautarzt 2013 (Acne Vulgaris...) : mTORC1 , the central hub of protein- and lipid biosynthesis, cell growth and proliferation, is activated by insulin, IGF-1 and branched-chain essential amino acids, especially leucine