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IGF2 — RPTOR
Text-mined interactions from Literome
Martin et al., Biol Reprod 2003
:
The resultant
mTOR signaling could
trigger polyamine,
insulin-like growth factor II , and nitric oxide production in blastocysts and the increased cell motility sometimes associated with synthesis of these bioactive molecules
Burgos et al., Domest Anim Endocrinol 2010
:
In addition,
IGF-1 stimulated
mTORC1 kinase activity toward 4E-BP1 in vitro
Melnik et al., Hautarzt 2013
(Acne Vulgaris...) :
mTORC1 , the central hub of protein- and lipid biosynthesis, cell growth and proliferation, is
activated by insulin,
IGF-1 and branched-chain essential amino acids, especially leucine