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IGF1 — RPS6KB1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Shah et al., Biochem J 2002
:
In the present study, we have shown that 4-amino-5- ( 4-methylphenyl ) -7- ( t-butyl ) pyrazolo [ 3,4-d ] pyrimidine ( PP1 ), a selective inhibitor of the Src family of non-receptor tyrosine kinases, interferes with the
activation of 70 and 85 kDa S6K gene products (
p70S6K1 and p85S6K1 ) by insulin,
insulin-like growth factor 1 , sodium orthovanadate and activated alleles of phosphoinositide 3-kinase and H-Ras
Kumar et al., Am J Physiol Endocrinol Metab 2002
(Acute Disease...) :
Pretreatment with a glucocorticoid receptor antagonist was unable to attenuate either the basal EtOH induced changes in eIF4E distribution or the impaired ability of
IGF-I to
stimulate S6K1 and S6 phosphorylation
Vary et al., Mol Cell Biochem 2005
:
IGF-I also
caused an increase in the phosphorylation of
S6K1
Vary et al., Am J Physiol Regul Integr Comp Physiol 2006
(Sepsis) :
In addition, phosphorylation of eIF4G and ribosomal protein
S6 kinase-1 ( S6K1 ) was also
enhanced by
IGF-I