Gene interactions and pathways from curated databases and text-mining

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IGF1 — RPS6KB1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Shah et al., Biochem J 2002 : In the present study, we have shown that 4-amino-5- ( 4-methylphenyl ) -7- ( t-butyl ) pyrazolo [ 3,4-d ] pyrimidine ( PP1 ), a selective inhibitor of the Src family of non-receptor tyrosine kinases, interferes with the activation of 70 and 85 kDa S6K gene products ( p70S6K1 and p85S6K1 ) by insulin, insulin-like growth factor 1 , sodium orthovanadate and activated alleles of phosphoinositide 3-kinase and H-Ras
Kumar et al., Am J Physiol Endocrinol Metab 2002 (Acute Disease...) : Pretreatment with a glucocorticoid receptor antagonist was unable to attenuate either the basal EtOH induced changes in eIF4E distribution or the impaired ability of IGF-I to stimulate S6K1 and S6 phosphorylation
Vary et al., Mol Cell Biochem 2005 : IGF-I also caused an increase in the phosphorylation of S6K1
Vary et al., Am J Physiol Regul Integr Comp Physiol 2006 (Sepsis) : In addition, phosphorylation of eIF4G and ribosomal protein S6 kinase-1 ( S6K1 ) was also enhanced by IGF-I