Gene interactions and pathways from curated databases and text-mining

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NOS1 — ROCK2

Text-mined interactions from Literome

Lang et al., Am J Physiol Heart Circ Physiol 2009 : Primary human aging may be associated with augmented Rho kinase ( ROCK ) -mediated contraction of vascular smooth muscle and ROCK mediated inhibition of nitric oxide synthase (NOS)
Hassona et al., Am J Physiol Heart Circ Physiol 2010 (Disease Models, Animal...) : The activation of Rho/ROCK led to the inhibition of endothelial nitric oxide synthase expression ( 39 + or - 5.4 % ; P < 0.05 ) and phosphorylation ( 35 + or - 4.5 % ; P < 0.05 ) but also an increase in myosin light chain 20 phosphorylation ( 372 %, P < 0.05 )