Qin et al., J Biol Chem 2006
(Alzheimer Disease) :
Consistently we found that the expression of exogenous human ( h ) SIRT1 in the brain of hSIRT1 transgenics also resulted in decreased ROCK1 expression and elevated alpha-secretase activity in vivo
Feng et al., PloS one 2013
:
Moreover, as a downstream signal molecule, ROCK1 was negatively regulated by SIRT1 ... Moreover, as a downstream signal molecule, ROCK1 was negatively regulated by SIRT1