Gene interactions and pathways from curated databases and text-mining

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CREB1 — RNF19A

Text-mined interactions from Literome

Tokunou et al., Arterioscler Thromb Vasc Biol 2001 : Inhibition of extracellular signal regulated protein kinase or inhibition of p38 mitogen activated protein kinase suppressed the thrombin induced CREB phosphorylation
Misra et al., J Biol Chem 2002 : Inhibition of Ca ( 2+ ) /calmodulin kinase, protein kinases A and C, tyrosine kinases, ribosomal S6 kinase, farnesyl transferase, extracellular signal regulated kinases 1/2, phosphatidylinositol 3-kinase, or p38 mitogen activated protein kinase markedly reduce alpha(2)M* induced phosphorylation of CREB , indicating a role for the p21(ras) dependent and phosphatidylinositol 3-kinase signaling pathways in regulating CREB activation by alpha(2)M*
Castro-Caldas et al., Mediators Inflamm 2003 : Furthermore, the cAMP antagonist, Rp-8-Br-cAMPS, and the specific p38 MAPK inhibitor, SB203580, effectively prevented both Dex induced, E2beta induced and dBcAMP induced CREB activation and ANXA1 synthesis
Zhang et al., Mol Cell Biol 2006 (MAP Kinase Signaling System) : Here we show that the induction of dynein light chain ( DLC ) by cAMP response element binding protein ( CREB ) is required for cAMP mediated inhibition of p38 activation
Murakami et al., Biol Chem 2006 (Inflammation...) : ACA abrogated ERK1/2 and JNK1/2, but not p38 activation , as well as the activation and transcriptional activation of NF-kappaB and CREB , whereas nobiletin allowed phosphorylation of these MAPKs, while it suppressed AP-1, NF-kappaB, and CREB activation
Lambert et al., J Immunol 2007 : Whereas p38 activation is critical for the phosphorylation of the transcription factor CREB , PI3K activation is required for the inactivation of glycogen synthase kinase 3beta ( GSK3beta ), an inhibitory kinase that can regulate CREB function
Deak et al., EMBO J 1998 : Mitogen- and stress activated protein kinase-1 ( MSK1 ) is directly activated by MAPK and SAPK2/p38 , and may mediate activation of CREB