Gene interactions and pathways from curated databases and text-mining

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RIPK2 — TLR4

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Lu et al., J Biol Chem 2005 : These data indicate that Rip2 is directly involved in the LPS/TLR4 signaling
Dorsch et al., Cell Signal 2006 : Stimulation of TLR 4 with its ligand lipopolysaccaride (LPS) leads to the activation of RIP2 kinase activity and its autophosphorylation
Hall et al., Eur J Immunol 2008 (Arenaviridae Infections) : RIP2 contributes to Nod signaling but is not essential for T cell proliferation, T helper differentiation or TLR responses