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MAPK14 — RIPK2

Pathways - manually collected, often from reviews:

• KEGG Shigellosis: RIPK2 → MAPK11/MAPK12/MAPK13/MAPK14 (protein-protein, activation)
  
• KEGG Tuberculosis: RIPK2 → MAPK11/MAPK12/MAPK13/MAPK14 (protein-protein, activation)
  

Text-mined interactions from Literome

Lamkanfi et al., J Biol Chem 2004 (MAP Kinase Signaling System) : These data demonstrate that caspase-1 contributes to inflammation by two distinct pathways : proteolysis of pro-IL-1beta, and RIP2 dependent activation of NF-kappaB and p38 MAPK mediated by the caspase recruitment domain
Windheim et al., Biochem J 2007 : We also show that RIP2 induces the activation of the protein kinase TAK1 ( transforming-growth-factor-beta activated kinase-1 ), that a dominant negative mutant of TAK1 inhibits RIP2 induced activation of JNK ( c-Jun N-terminal kinase ) and p38alpha MAPK , and that signalling downstream of NOD2 or RIP2 is reduced by the TAK1 inhibitor ( 5Z ) -7-oxozeaenol or in TAK1-deficient cells
Duprez et al., J Biol Chem 2012 (MAP Kinase Signaling System...) : Depending on the cell type and conditions, RIPK1 mediates MAPK and NF-?B activation as well as cell death
Taxman et al., J Dent Res 2012 (Chronic Periodontitis...) : We show that pharmacological inhibition of RIPK2 represses PGE ( 2 ) secretion, and RNAi mediated silencing of RIPK2 leads to diminished MAPK activation and PGE ( 2 ) secretion