Gene interactions and pathways from curated databases and text-mining

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AKT1 — RIPK1

Text-mined interactions from Literome

Duong et al., Cancer Res 2006 (Breast Neoplasms) : Given the importance of coactivators in ER transcriptional activity, we further investigated the possible involvement of steroid receptor coactivator 1 (SRC1) and glucocorticoid receptor interacting protein 1 ( GRIP1 ) in AKT regulation of ER beta
Park et al., Cancer Res 2009 (Brain Neoplasms...) : RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN ... Our data suggest that RIP1 activates PI3K-Akt using dual mechanisms by removing the two major brakes on PI3K-Akt activity