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AKT1 — RIPK1
Text-mined interactions from Literome
Duong et al., Cancer Res 2006
(Breast Neoplasms) :
Given the importance of coactivators in ER transcriptional activity, we further investigated the possible
involvement of steroid receptor coactivator 1 (SRC1) and glucocorticoid
receptor interacting protein 1 ( GRIP1 ) in
AKT regulation of ER beta
Park et al., Cancer Res 2009
(Brain Neoplasms...) :
RIP1 activates
PI3K-Akt via a dual mechanism involving NF-kappaB mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN ... Our data suggest that
RIP1 activates
PI3K-Akt using dual mechanisms by removing the two major brakes on PI3K-Akt activity