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MAPK3 — RHO

Text-mined interactions from Literome

Zhu et al., Circulation 1999 : DM-induced activation of ERKs was also inhibited by overexpression of dominant negative mutants of Ras ( D.N.Ras ), and the p38 MAPK activation was attenuated by D.N.Rho
Ashida et al., J Biol Chem 2001 : Further, C3 exoenzyme and the Rho kinase inhibitor blocked MCP-1 dependent p38-MAPK activation
Reyes-Reyes et al., J Cell Sci 2001 (Leukemia) : In addition, a dominant negative form of Rho augmented NF-kappaB activation and blocked MAPK activation, implying that these two pathways are in competition with each other
Ishizuka et al., J Immunol 2001 : Both p38 MAPK activation and Rho dependent activation of Rho associated coiled-coil forming protein kinase may be required for Fc ( epsilon ) RI-mediated cell migration
Pawlak et al., Mol Biol Cell 2002 (MAP Kinase Signaling System) : Investigating the mechanism underlying this phenotypic reversion, we found that the sustained MAPK signaling resulting from Ras-transformation down-regulated the expression of ROCKI and Rho-kinase , two-Rho effectors required for stress fiber formation, at the post-transcriptional level
Zhong et al., Blood 2003 (MAP Kinase Signaling System) : Rac and Cdc42, but not Ras or Rho , were responsible for this MAPK/ERK activation
Stepan et al., Am J Physiol Gastrointest Liver Physiol 2004 : In contrast, G17 stimulated MAPK activation was blocked by > 80 % by dominant negative Ras but not by dominant negative Rho and Cdc42
Kim et al., Eur J Pharmacol 2005 (Hypertension) : Thus, basal vascular tone is elevated by the altered activation of MAPK in DOCA-salt hypertensive rats, and this is regulated by PKC, but not by Rho or intracellular Ca2+
Jia et al., Biol Cell 2006 : The localized activation of an autocrine HGF/c-Met loop regulates Rho/ROCK activation of p38 MAPK signalling to stimulate both membrane blebbing and pseudopod formation
Yu et al., J Neurosci Res 2007 : Blocking MAPK signaling diminishes the blue light induced increases in rhodopsin promoter expression, but this treatment has no effect on white light mediated rhodopsin promoter expression ... Together, the data suggest that MAPK and PKA regulate rhodopsin transcription through parallel signal transduction pathways
Quinlan et al., American journal of physiology. Renal physiology 2008 (Ureteral Obstruction) : Key among these are 1 ) the activation of Rho , consequent cytoskeletal rearrangements, and downstream increases in focal adhesion assembly ; and 2 ) phospholipase activation and resultant mitogen activated protein kinase activation
Wu et al., Translational research : the journal of laboratory and clinical medicine 2013 (Inflammation...) : In macrovascular ECs, pharmacologic inhibition of Rho kinase with Y27632 suppressed p38 MAP kinase cascade activation significantly, whereas inhibition of p38 MAPK with SB203580 had no effect on Rho activation ... In contrast, inhibition of p38 MAPK in microvascular ECs suppressed LTA/PepG induced activation of Rho , whereas the Rho inhibitor suppressed activation of p38 MAPK