Gene interactions and pathways from curated databases and text-mining

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CASP7 — RHO

Text-mined interactions from Literome

Hippenstiel et al., Am J Physiol Lung Cell Mol Physiol 2002 : In summary, inhibition of Rho in endothelial cells activates caspase-9- and -3-dependent apoptosis, which can be antagonized by cAMP elevation
He et al., Cell Signal 2008 : Since in other systems G proteins of the Rho family inhibit apoptosis via interaction with proteins of the Bcl-2 family, leading to changes in caspase activities, we have compared the role of Rho family G proteins in regulation of Bcl-2-like ( Bad/Bax/Bcl-xl ) protein expression and caspase 3 activation by Ggly and Gamide