Gene interactions and pathways from curated databases and text-mining

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IGF1 — RENBP

Text-mined interactions from Literome

Zheng et al., Mol Med 2001 (Diabetes Mellitus, Type 1...) : B ) LZ stimulated the uptake and degradation of ( 125 ) I-labeled AGE-BSA and ( 25 ) I-human serum AGE by Mf, while suppressing AGE induced TNFalpha and IGF-I production
McCarthy et al., Acta Diabetol 2001 : In the present study, we investigated the effects of AGE-proteins on the secretion of insulin-like growth factor-I (IGF-I) and its binding proteins ( IGFBPs ) by both osteoblast-like cell lines
Pugliese et al., Diabetes 1997 : Co-incubation of BSA-AGE with anti-AGE-R1, but not with pre-immune serum, prevented AGE induced increases in IGF-I , TGF-beta1, and ECM production or gene expression ; anti-AGE-R1 also reduced growth factor and matrix synthesis in cells grown on BSA