Gene interactions and pathways from curated databases and text-mining

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CHUK — RELB

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Demicco et al., Mol Cell Biol 2005 (Breast Neoplasms...) : Constitutively active IKKalpha induced p52, RelB , and cyclin D1 in untransformed mammary epithelial cells
Schneider et al., EMBO J 2006 : IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression
Yang et al., Am J Respir Cell Mol Biol 2009 (Pneumonia...) : RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke ... Transient transfection of dominant negative IkappaB-kinase-alpha and double mutants of NF-kappaB inducing kinase partially attenuated the CS extract mediated loss of RelB in B cells and normalized the increased RelB level in macrophages
Baud et al., Med Sci (Paris) 2008 (Lymphoma...) : It has been shown that this pathway mainly controls the activity of RelB , a member of the NF-kappaB family, and its activation requires IKKalpha , one of the two catalytic subunits of the IKK complex
Penzo et al., J Immunol 2010 : In addition, HMGB1 modestly induces noncanonical IKKalpha dependent p52 nuclear translocation and p52/RelB target gene expression