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AKT1 — RBP4
Text-mined interactions from Literome
Farias et al., Oncogene 2005
(Breast Neoplasms...) :
Cellular
retinol binding protein-I inhibits
PI3K/Akt signaling through a retinoic acid receptor dependent mechanism that regulates p85-p110 heterodimerization
Takebayashi et al., Biochem Biophys Res Commun 2011
:
The
effects of
RBP4 on nitric oxide ( NO ) and insulin stimulated endothelin-1 (ET-1) secretion and on phosphorylation ( p ) of
Akt , endothelial NO synthetase (eNOS), and extracellular signal regulated kinase ( ERK ) 1/2 were investigated in bovine vascular aortic endothelial cells ( BAECs ) ...
RBP4 significantly
increased p-Akt and p-eNOS production, and significantly inhibited p-ERK1/2 production ... Triciribine, an Akt inhibitor, and wortmannin significantly inhibited
RBP4 induced
p-Akt and p-eNOS production