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AKT1 — RB1

Pathways - manually collected, often from reviews:

• BioCarta il-2 receptor beta chain in t cell activation: RB/E2F-1 complex (E2F1-RB1) → AKT (AKT1) (modification, collaborate)

Text-mined interactions from Literome

Shang et al., J Endocrinol 2008 : Meanwhile, Rb(1) increased the phosphorylation of insulin receptor substrate-1 and protein kinase B (PKB) , and stimulated phosphatidylinositol 3-kinase (PI3K) activity in the absence of the activation of the insulin receptor
Hashimoto et al., Evidence-based complementary and alternative medicine : eCAM 2012 : Rb1 increased phosphorylation levels of ERK1/2 or Akt in MPP ( + ) -treated PC12 cells, while it reduced phosphorylated p38 or SAPK/JNK