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Terada et al., Biochem Biophys Res Commun 2000
:
Conditional activation of c-Raf-1 also suppressed caspase-3 activation and subsequent cell death without affecting Akt activity, providing further evidence for a PI3-K/Akt independent mechanism
Jesenberger et al., J Exp Med 2001
:
Raf-1 degradation is SipB- and caspase-1 dependent , and is prevented by proteasome inhibitors
Cornelis et al., Oncogene 2005
(Fibrosarcoma) :
Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1 ... These results suggest an important role for caspase-9 mediated cleavage of Raf-1 in the negative feedback regulation of hematopoietic cell apoptosis induced by growth factor withdrawal
Tian et al., Int J Oncol 2006
:
In our efforts to understand the mechanism by which Raf-1 inhibits caspase activation, we discovered a novel interaction between Raf-1 and XIAP