Gene interactions and pathways from curated databases and text-mining

◀ Back to CASP5

CASP5 — RAD51

Text-mined interactions from Literome

Huang et al., Mol Cell Biol 1999 : Role for caspase mediated cleavage of Rad51 in induction of apoptosis by DNA damage
Broustas et al., J Biol Chem 2004 (Prostatic Neoplasms) : BRCC2 , a novel BH3-like domain containing protein, induces apoptosis in a caspase dependent manner
Kim et al., Autophagy 2008 (Disease Models, Animal...) : To test this hypothesis, combinations of Z-DEVD ( caspase-3 inhibitor ), RAD001 ( mTOR inhibitor ) and irradiation were tested in cell and mouse models
Brown et al., Radiat Res 2008 : We further showed that caspase 3 cleavage of Rad51 resulted in a functional decrease in Rad51 strand exchange activity and that inhibition of caspase 3 activity increased Rad51 protein levels and Rad51 foci
Wu et al., Evidence-based complementary and alternative medicine : eCAM 2013 : Compared to FIS treatment alone of COLO205 cells, GA and RAD significantly enhanced FIS induced cytotoxicity, increased expression of cleaved caspase-3 and the PAPR protein, and produced a greater density of DNA ladder formation