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MAPK3 — RAC3

Text-mined interactions from Literome

Mainiero et al., Immunity 2000 (MAP Kinase Signaling System) : Finally, we provide direct evidence that p95 Vav and Rac control the activation of p38 MAPK triggered by beta1 integrins
Versteeg et al., J Biol Chem 2000 : In turn Rac mediates p38 mitogen activated protein ( MAP ) kinase activation and cytoskeletal reorganization, whereas factor VIIa induced p42/p44 MAP kinase stimulation required PI3K enzymatic activity but was not inhibited by dominant negative Rac proteins
Zhong et al., Blood 2003 (MAP Kinase Signaling System) : Rac and Cdc42, but not Ras or Rho, were responsible for this MAPK/ERK activation ... We conclude from these data that Rac/Cdc42 dependent activation of MAPK/ERK is a critical event in the immediate phagocytic response of PMNs to microbial challenge
Chen et al., Mol Microbiol 2004 (MAP Kinase Signaling System) : Co-expression of DARas with dominant active Rac ( DARac ) stimulates MAPK activation and restores the wild-type phenotype
Kesavapany et al., J Neurosci 2004 : p35/cyclin dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 ( RasGRF2 ) mediates Rac dependent Extracellular Signal regulated kinase 1/2 activity, altering RasGRF2 and microtubule associated protein 1b distribution in neurons
Nishida et al., J Biol Chem 2005 : Dominant negative Rac inhibited angiotensin II-stimulated ROS production, JNK activation, and p38 MAPK activation but did not affect ERK activation
Goparaju et al., Mol Cell Biol 2005 : Although S1P(2) deletion had no significant effect on tyrosine phosphorylation of the PDGF receptors or activation of extracellular signal regulated kinase 1/2 or Akt induced by PDGF, it reduced sustained PDGF dependent p38 phosphorylation and markedly enhanced Rac activation
Otis et al., Mol Cell Endocrinol 2007 : The increase in cell protein content induced by Ang II entails formation of a cortical actin ring and Rac dependent activation of p42/p44(mapk) and p38 MAPK ... The increase in cell protein content induced by Ang II entails formation of a cortical actin ring and Rac dependent activation of p42/p44(mapk) and p38 MAPK
Bachmann et al., Proc Natl Acad Sci U S A 2013 (MAP Kinase Signaling System) : Our findings offer additional mechanistic insights how ß-adrenergic receptor controlled PKA activities enhance GTP-Rac mediated activation of nuclear Erk1/2 signaling