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IRS4 — RAC1

Pathways - manually collected, often from reviews:

• WikiPathways Insulin Signaling: SHC3/IRS1/IRS2/SHC1/IRS4/SHC2/GAB1 → RAC1/GRB2/SOS1/RAC2/RRAD/GRB14/SOS2/RAF1/HRAS/GRB10 (activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 23 proteins (association, tandem affinity purification) Daulat et al., Mol Cell Proteomics 2007