Gene interactions and pathways from curated databases and text-mining

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CXCR4 — RAC1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Zoughlami et al., Blood 2012 (HIV Infections) : We show in different cell types, including CD34 ( + ) hematopoietic stem and progenitor cells, that inhibition of Rac1 causes a reversible conformational change in CXCR4 , but not in the related receptors CXCR7 or CCR5
Huang et al., PloS one 2012 (Breast Neoplasms...) : Interference with the activation of Rac1 , a downstream target of HGF, prevented the HGF induced increase in PKC? activity and CXCR4 levels