Gene interactions and pathways from curated databases and text-mining

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PTPN6 — STAT3

Text-mined interactions from Literome

Kim et al., Cancer Lett 2008 : The activation of ILs/STAT3 signaling can amplify CD44 function, and vice versa, and induce protein-tyrosine phosphatase SHP1 activity by a negative feedback mechanism
Yuan et al., J Biol Chem 2010 (Breast Neoplasms...) : Furthermore, PTPN9 WT expression specifically impairs EGF induced STAT3 and STAT5 activation, and inhibits the cell growth in soft agar