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MAPK14 — PTPN1

Text-mined interactions from Literome

Egawa et al., J Biol Chem 2001 (Carcinoma, Hepatocellular...) : In both cells, PTP1B overexpression blocked insulin stimulated tyrosine phosphorylation of the insulin receptor and IRS-1 by more than 70 % and resulted in a significant inhibition of the association between IRS-1 and the p85 subunit of phosphatidylinositol 3-kinase and Akt phosphorylation as well as mitogen activated protein kinase phosphorylation
Shimizu et al., Endocrinology 2002 : Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen activated protein kinase in 3T3-L1 adipocytes ... Overexpression of a wild-type PTP1B in L1 adipocytes as well as in L6 myocytes, led to a profound decrease in insulin stimulated phosphorylation of MAPK
Nakamura et al., Circ Res 2008 (Disease Models, Animal...) : VEGF induced p38 mitogen activated protein kinase phosphorylation and EC migration are not affected by PTP1B overexpression or knockdown
Liu et al., Mol Cell Biol 1998 (Cell Transformation, Neoplastic) : Expression of WT-PTP1B reduces formation of p130Cas-Crk complexes and inhibits mitogen activated protein kinase activation by Src and Crk