Gene interactions and pathways from curated databases and text-mining

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MAPK6 — PTK2B

Text-mined interactions from Literome

Pandey et al., J Biol Chem 1999 : Overexpression of RAFTK leads to the activation of p38 MAPK ... We observe that the dominant negative mutant of MKK3 but not of MKK6, SEK1, or MEK1 inhibits RAFTK induced p38 MAPK activity
Kumar et al., J Biol Chem 1999 : Overexpression of RAFTK induces activation of c-Jun amino-terminal kinase ( also known as stress activated protein kinase ), mitogen activated protein kinase ( MAPK ), and p38 MAPK ... Furthermore, in contrast to the phosphatase-dead SHPTP1 C453S mutant, overexpression of wild-type SHPTP1 blocks interaction of RAFTK with the SH2-domain of c-Src and inhibits RAFTK mediated MAPK activation
Hatch et al., Blood 1998 (Leukemia, Monocytic, Acute) : Inhibition of RAFTK by a dominant negative kinase mutant reduced CSF-1/M-CSF induced MAPK activity