Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF2

IGF2 — PTH

Text-mined interactions from Literome

Pereira et al., Endocrinology 1999 : PTH induces the synthesis of insulin-like growth factor I (IGF-I) and regulates the expression of IGF binding proteins ( IGFBP ) in osteoblast cultures
Erclik et al., J Mol Endocrinol 2005 (Osteosarcoma) : Activation of the insulin-like growth factor binding protein-5 promoter by parathyroid hormone in osteosarcoma cells requires activation of an activated protein-2 element
Wang et al., J Endocrinol 2006 : However, PTH increased the mRNA levels of IGF-I and IGF-IR only in the bones of male mice
Tørring et al., Endocrinology 1991 : Taken with the known effects of PTH on IGF production in bone cells, the data suggest that PTH and PTHrP may modulate local IGF action in bone through the regulation of specific IGFBP availability
Linkhart et al., Endocrinology 1991 (Bone Resorption) : In a previous study we found that PTH stimulated bone resorption and release of insulin-like growth factor-I (IGF-I) and IGF-II from cultured neonatal mouse calvaria ... The results of this and the previous study suggest that PTH , TGF beta, and 1,25- ( OH ) 2D3 differentially regulate mouse calvarial cell IGF-I and IGF-II production
Linkhart et al., Endocrinology 1989 : Calcitonin inhibited PTH stimulated resorption, but had no effect on PTH stimulation of IGF-I and IGF-II release, suggesting that PTH effects on IGF-I and IGF-II release were not dependent on resorption
Nasu et al., FEBS Lett 1997 : Stimulatory effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 on insulin-like growth factor binding protein-5 mRNA expression in osteoblastic UMR-106 cells : the difference between transient and continuous treatments
McCarthy et al., J Biol Chem 1997 : In osteoblasts, IGF-I synthesis is enhanced by parathyroid hormone and prostaglandin E2 ( PGE2 ) through cAMP activated protein kinase