Gene interactions and pathways from curated databases and text-mining

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CREB1 — PTCH1

Text-mined interactions from Literome

Castellone et al., Cancer Res 2009 (Carcinoma, Papillary...) : Moreover, through the ERK pathway, RET/PTC stimulates cyclic AMP-responsive element binding protein ( CREB ) phosphorylation and promotes the formation of a beta-catenin-CREB-CREB binding protein/p300 transcriptional complex ... Moreover, through the ERK pathway, RET/PTC stimulates cyclic AMP-responsive element binding protein ( CREB ) phosphorylation and promotes the formation of a beta-catenin-CREB-CREB binding protein/p300 transcriptional complex
Xing et al., J Biol Chem 1998 (Carcinoma, Papillary...) : We also showed that RET/PTC1 , 2A/RET, and 2B/RET induce ELK-, cAMP-responsive element binding protein ( CREB ), or JUN mediated gene expression in PC12 cells, and these three signaling events are mediated by phosphorylated Tyr294 and phosphorylated Tyr451 binding sites in RET/PTC1