Gene interactions and pathways from curated databases and text-mining

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PRKAR2A — PRL

Text-mined interactions from Literome

Brosens et al., Endocrinology 1999 : Human endometrial stromal ( ES ) cells in culture express PRL , a marker of decidualization, in response to sustained activation of protein kinase A (PKA)
Christian et al., J Biol Chem 2002 : Reporter gene studies showed that FKHR potently enhances PKA dependent activation of the tissue-specific decidual prolactin ( dPRL ) promoter, a major differentiation marker in human ES cells
Kimata-Hayashi et al., Endocr J 2005 (Pituitary Neoplasms...) : PKA inhibitor attenuated adrenomedullin induced prolactin release
Hong et al., Biochem Mol Biol Int 1997 : We suggest that PRL negatively regulates the PCNA-gene transcription by interfering with the cAMP/PKA mediated induction of CREB binding to the CRE-sequences and thereby suppresses DNA synthesis in regenerating rat liver
Zanger et al., Mol Endocrinol 1999 : The pituitary-specific transcription factor, Pit-1, is necessary to mediate protein kinase A (PKA) regulation of the GH, PRL , and TSH-beta subunit genes in the pituitary