Gene interactions and pathways from curated databases and text-mining

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NPY — PRKAR1A

Text-mined interactions from Literome

Misra et al., Biol Psychiatry 2006 : Interestingly, PKA activator coinfusion with PKA inhibitor into the NAc shell significantly normalized the PKA inhibitor induced decreases in the protein levels of PKA-Calpha and p-CREB as well as of NPY in the NAc shell of rats
Wand et al., J Clin Invest 2005 (Alcohol-Induced Disorders, Nervous System...) : Alcohol intake by these animals was shown to increase PKA dependent CREB phosphorylation and thereby NPY expression, subsequently ameliorating anxiety-like behavior
Hsieh et al., Am J Physiol Endocrinol Metab 2007 (Anorexia) : To determine whether PKA or CREB was involved in the anorectic response, intracerebroventricular infusions of antisense oligonucleotide ( or missense control ) were performed 60 min before daily AMPH treatment in conscious rats, and results showed that either PKA or CREB knockdown could block AMPH induced anorexia as well as restore NPY mRNA level, indicating the respective involvement of PKA and CREB signaling in the regulation of NPY gene expression
Hsieh et al., Physiol Genomics 2007 (Anorexia...) : Aims of this study were to investigate whether protein kinase A (PKA) signaling is involved in regulating NPY gene expression and PPA induced anorexia ... Results also showed that PKA knock-down could block PPA induced anorexia as well as restore NPY mRNA level, indicating the involvement of PKA signaling in the regulation of NPY gene expression