Gene interactions and pathways from curated databases and text-mining

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NOS1 — PRKACG

Text-mined interactions from Literome

Yu et al., Brain Res Mol Brain Res 2002 (Synaptic Transmission) : Our data indicate that the protein inhibitor of nNOS (PIN) binds to protein kinase A inhibitors ( PKIs ), which suggests that PKIs, together with PIN, might mediate the phosphorylation of nNOS by PKA
Jaureguiberry et al., Peptides 2004 : The stimulatory effect of ETs on NOS activity was inhibited in the presence of PLC, PKC, PKA and CaMK-II inhibitors ( U-73122, GF-109203X, H-89 and KN-62, respectively ), and the IP3 receptor selective antagonist, 2-APB
Rodriguez et al., Anim Reprod Sci 2005 : These results indicate that NO* may be generated by a sperm NOS during heparin induced capacitation and that exogenous NO* acts as a capacitation inducer and involves the participation of PKA , PKC and PTK as part of the intracellular mechanisms that lead to capacitation in cryopreserved bull spermatozoa
Queen et al., J Physiol 2006 : beta ( 2 ) AR activation also increased NOS activity and phosphorylation of NOS-3 on serine-1177, and these increases were attenuated by inhibition of protein kinase A (PKA) , phosphatidylinositol 3-kinase (PI3K) or Akt, and abolished by coinhibition of PKA and Akt
Ohnishi et al., J Neurochem 2008 : These results demonstrate that PACAP stimulated nNOS translocation mediated by PKA and PKC via PAC(1)-receptor ( a PACAP receptor ) and suggest cross-talk between PACAP and NMDA for nNOS activation by Src dependent phosphorylation of NMDA receptors
Yen et al., J Biomed Sci 2011 : The possibility of PKA dependent nNOS activation was substantiated by immunohistochemical demonstration of co-localization of PKA and nNOS in putative NTS neurons
Song et al., Int J Mol Med 2012 : The phosphorylation levels of nNOS at Ser1412, induced by activation of Akt/PKB or CaM-K II, but not by PKA signaling, were reduced by pre-treatment with the NO donor diethylamine-NONOate ... Furthermore, the levels of phosphorylation of nNOS at Ser1412, induced by Akt/PKB or CaM-K II but not by PKA signaling, were enhanced by inhibition of nNOS activity with 7-nitroindazole
Wang et al., Exp Neurol 2013 : Involvement of PKA dependent upregulation of nNOS-CGRP in adrenomedullin initiated mechanistic pathway underlying CFA induced response in rats