Gene interactions and pathways from curated databases and text-mining

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EPO — PRKAA2

Text-mined interactions from Literome

Li et al., Am J Med Sci 2011 (Myocardial Infarction) : More importantly, under MI conditions, EPO further increased the phosphorylation of AMPK and suppressed the activation of nuclear factor kappa B
Su et al., J Cell Physiol 2012 : Inhibition of AMPK activation by compound C or dominant negative AMPK mutant abrogated the EPO induced increase in the phosphorylation of AMPK , ACC, and eNOS, as well as nitric oxide ( NO ) production
Wang et al., Int J Biochem Cell Biol 2013 : Erythropoietin also increases AMPK , which induces PGC-1a and stimulates slow oxidative fiber formation ... These data suggest that erythropoietin contributes to skeletal muscle fiber programming and metabolism, and increases PGC-1a and AMPK activity during muscle development directly to affect the proportion of slow/fast twitch myofibers in mature skeletal muscle