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BECN1 — PRKAA2
Text-mined interactions from Literome
Matsui et al., Circ Res 2007
(Myocardial Ischemia) :
In contrast, autophagy during reperfusion was accompanied by upregulation of
Beclin 1 but not by
activation of
AMPK
Wang et al., J Biol Chem 2009
:
Our findings thus propose that the
AMPK-MEK/ERK-TSC-mTOR pathway
regulation of
Beclin 1 represents different thresholds responsible for a protective or destructive autophagy
He et al., Diabetes 2013
(Diabetes Mellitus, Experimental...) :
We hypothesized that AMPK induced autophagy ameliorates diabetic cardiomyopathy by inhibiting cardiomyocyte apoptosis and examined the
effects of
AMPK on the interaction between
Beclin1 and Bcl-2, a switch between autophagy and apoptosis, in diabetic mice and high glucose treated H9c2 cardiac myoblast cells