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IL5 — PRDM1

Text-mined interactions from Literome

Yasue et al., Int Immunol 1999 : Furthermore, stimulation of splenic B cells with IL-5 together with CS/2 induces Blimp-1 expression and differentiation into Ig-producing cells
Tsukamoto et al., Biochem Biophys Res Commun 2005 : IL-5 induces AID and Blimp-1 expression in CD38- and CD40 activated B-2 cells, leading to mu to gamma1 CSR at DNA level and IgG1 production
Takatsu et al., Adv Immunol 2009 (Hypersensitivity) : IL-5 critically regulates homeostatic proliferation and survival of and natural antibody production by B-1 cells, and enhances the AID and Blimp-1 expression in activated B-2 cells leading to induce mu to gamma1 class switch recombination and terminal differentiation to IgM- and IgG1 secreting plasma cells, respectively