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MAPK3 — PPP5C

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 35 proteins (association, anti tag coimmunoprecipitation) Behrends et al., Nature 2010
• IRef Intact Interaction: Complex of 29 proteins (association, anti tag coimmunoprecipitation) Behrends et al., Nature 2010

Text-mined interactions from Literome

Suzuki et al., Surgery 2006 (Disease Models, Animal...) : PPT or E2 also prevented T-H mediated activation of MAPK in KC
Chen et al., Free Radic Biol Med 2008 : Overexpression of PP2A or PP5 partially prevented Cd-induced activation of Erk1/2 and JNK, as well as cell death
Cignarella et al., J Pharmacol Exp Ther 2009 (Diabetes Mellitus, Experimental...) : However, extracellular signal regulated kinase 1/2 signaling was activated by DPN but not by PPT in cytokine treated SMCs
Hershberger et al., J Steroid Biochem Mol Biol 2009 (Carcinoma, Non-Small-Cell Lung...) : PPT and DPN increased MAPK phosphorylation ( 2.5-fold and 3.7-fold, respectively )
Sanchez-Ortiz et al., J Neurochem 2009 (Alzheimer Disease...) : In contrast, over-expression of PP5 , but not the inactive mutant, PP5 ( H304Q ), prevented MAPK phosphorylation and neurotoxicity induced by Abeta
Han et al., Carcinogenesis 2012 : Overexpression of PP2A or PP5 partially prevented curcumin induced activation of JNK and Erk1/2 phosphorylation as well as cell death