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PPARG — TLR4
Text-mined interactions from Literome
Rousseaux et al., J Soc Biol 2006
(Colitis, Ulcerative...) :
Toll Like Receptor-4 (TLR-4) , responsible for the recognition of bacterial motif as lipopolysaccharide (LPS), is implicated in
PPARgamma regulation and its anti-inflammatory properties
Necela et al., Immunology 2008
:
Our data indicate that activation of
TLR4 inhibits
PPARgamma mRNA synthesis by an NF-kappaB dependent mechanism
Zhang et al., J Neuroimmunol 2010
:
In LPS treated primary SCs, retreatment with PPAR-gamma agonist remitted the increase of iNOS, p38 phosphorylation and
TLR4 , MyD88,
augmented the expression of
PPAR-gamma and localization in nuclear