Gene interactions and pathways from curated databases and text-mining

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PPARG — TLR4

Text-mined interactions from Literome

Rousseaux et al., J Soc Biol 2006 (Colitis, Ulcerative...) : Toll Like Receptor-4 (TLR-4) , responsible for the recognition of bacterial motif as lipopolysaccharide (LPS), is implicated in PPARgamma regulation and its anti-inflammatory properties
Necela et al., Immunology 2008 : Our data indicate that activation of TLR4 inhibits PPARgamma mRNA synthesis by an NF-kappaB dependent mechanism
Zhang et al., J Neuroimmunol 2010 : In LPS treated primary SCs, retreatment with PPAR-gamma agonist remitted the increase of iNOS, p38 phosphorylation and TLR4 , MyD88, augmented the expression of PPAR-gamma and localization in nuclear