Gene interactions and pathways from curated databases and text-mining

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IGF1 — POU1F1

Text-mined interactions from Literome

Romero et al., Mol Cell Biol 2012 (Weight Gain) : IGF-1 significantly inhibits basal GH mRNA levels but not POU1F1 levels ... We hypothesized that IGF-1 receptor (IGF-1R) signaling disrupts the POU1F1/CBP complex to inhibit gene expression
Castillo et al., Endocrinology 1997 : Thus, a different effect of IGF-1 on the expression of GHF-1/Pit-1 in GH3 and GH4C1 cells is likely involved in the different regulation of GH and PRL gene in both cell types