Gene interactions and pathways from curated databases and text-mining

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MLST8 — PML

Pathways - manually collected, often from reviews:

  • NCI Pathway Database mTOR signaling pathway: PML (PML) → mTORC1/PRAS40/DEPTOR/PML complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR-PML) (modification, collaborate)
    Bernardi et al., Nature 2006
    Evidence: mutant phenotype, assay, physical interaction
  • NCI Pathway Database mTOR signaling pathway: PML (PML) → mTORC1/PRAS40/DEPTOR complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR) (modification, collaborate)
    Bernardi et al., Nature 2006
    Evidence: mutant phenotype, assay, physical interaction
  • NCI Pathway Database mTOR signaling pathway: mTORC1/PRAS40/DEPTOR/PML complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR-PML) → mTORC1/PRAS40/DEPTOR complex (MTOR-MLST8-AKT1S1-DEPTOR-RPTOR) (modification, collaborate)
    Bernardi et al., Nature 2006
    Evidence: mutant phenotype, assay, physical interaction