Gene interactions and pathways from curated databases and text-mining

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MLST8 — PLD3

Text-mined interactions from Literome

Yoon et al., J Cell Sci 2008 : Instead, PLD1 positively regulates mTOR signaling leading to the production of IGF2, an autocrine factor instrumental for the initiation of satellite cell differentiation
Suryawan et al., J Appl Physiol 2010 : Our results suggest that the enhanced activation of mTORC1 in muscle of neonatal pigs is in part due to regulation by PRAS40, PLD1 , and the Rag GTPases
Arous et al., Diabetologia 2011 : Oleate mediated mTORC1 activation required phospholipase D activation, which produces phosphatidic acid and is known to render mTORC1 rapamycin resistant
Razmara et al., Cell communication and signaling : CCS 2013 : In addition, PDGF-BB induced activation of mTORC1 , as measured by phosphorylation of the downstream S6 protein, was dependent on phospholipase D ( PLD ) ... mTORC1 is activated in a PLD dependent manner and promotes phosphorylation of the S6 protein, whereas mTORC2, in concert with PLC? signaling, promotes Akt phosphorylation