Gene interactions and pathways from curated databases and text-mining

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MAPK6 — PLD2

Text-mined interactions from Literome

Min et al., Exp Mol Med 2002 (MAP Kinase Signaling System) : Interestingly, specific inhibition of p38 MAPK with SB203580 attenuated pervanadate induced PLD activation
Cummings et al., Mol Cell Biochem 2002 : In pulmonary epithelial and vascular endothelial cells, a wide variety of agonists stimulate PLD and involve Src kinases, p-38 mitogen activated protein kinase , calcium and small G proteins
Grab et al., Biochim Biophys Acta 2004 : Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated MAPK activation, Cox-2 and IL-8 expression ... Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated MAPK activation, Cox-2 and IL-8 expression
Fernández-Tome et al., Biochem Biophys Res Commun 2004 : p44/42 ( ERK1/2 ) MAPK and PLD activation by PGD2 preserves papillary phosphatidylcholine homeostasis
Li et al., J Pharmacol Exp Ther 2005 : These data indicate that Ang II-stimulated Akt activity is mediated by cPLA(2) dependent, p38 MAPK regulated PLD(2) activation and EGFR transactivation
Hamdi et al., Biochim Biophys Acta 2008 (MAP Kinase Signaling System) : As a functional consequence of this PLD2 dependent MAPK activation, interleukin-2 production evoked by PMA/ionomycin stimulation or CD3/CD28 engagement was enhanced in the two T-cell lines overexpressing PLD2
Park et al., J Biol Chem 2009 : Der f 2-induced PLD activation was attenuated by PLCgamma inhibitors ( U73122 and PAO ), PKCalpha inhibitors ( RO320432 and GO6976 ), and p38 MAPK inhibitors ( SB203580 and SB202190 )
Cho et al., Mol Cell Biol 2011 : In contrast, ectopic expression of wild-type PLD2 enhanced Ras and MAPK activation in response to therapeutic levels of lovastatin
Ito et al., J Neurochem 1998 : Possible involvement of mitogen activated protein kinase in phospholipase D activation induced by H2O2, but not by carbachol, in rat pheochromocytoma PC12 cells