Gene interactions and pathways from curated databases and text-mining

◀ Back to IGF2

IGF2 — PLAG1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: IGF2 → PLAG1 (increases)
    Evidence: Table 2. Identification of genes consistently and significantly induced by PLAG1. Genes induced by at least 2.5-fold in each of 2 sets of Plag1 overexpressing clones compared to 2 sets of control cells.

Text-mined interactions from Literome

Zatkova et al., Genes Chromosomes Cancer 2004 (Hepatoblastoma...) : Thus, our results provide evidence that PLAG1 overexpression may be responsible for the frequently observed up-regulation of IGF2 in hepatoblastoma and therefore may be implicated in the molecular pathogenesis of this childhood neoplasia
Zheng et al., J Biol Chem 2005 : Further study showed that sumoylation inhibits PLAG1 induced IGF-II expression in reporter assays