Gene interactions and pathways from curated databases and text-mining

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IL5 — PIN1

Text-mined interactions from Literome

Lee et al., Nat Cell Biol 2009 (Chromosomal Instability) : Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance ... However, little is known about the role of Pin1 in telomere regulation or the modulation of TRF1 by upstream signals ... Pin1 inhibition renders TRF1 resistant to protein degradation, enhances TRF1 binding to telomeres, and leads to gradual telomere loss in human cells and in mice
Oh et al., J Immunol 2013 (Asthma) : Pin1 was activated by IL-5, whereas simultaneous IL-5 and anti-Fas treatment modestly reduced peptidyl isomerase activity but induced Pin1 to associate with FADD after its phosphorylation at Ser ( 194 )