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IL5 — PIN1
Text-mined interactions from Literome
Lee et al., Nat Cell Biol 2009
(Chromosomal Instability) :
Essential
role of
Pin1 in the regulation of
TRF1 stability and telomere maintenance ... However, little is known about the
role of
Pin1 in telomere regulation or the modulation of
TRF1 by upstream signals ...
Pin1 inhibition renders TRF1 resistant to protein degradation,
enhances TRF1 binding to telomeres, and leads to gradual telomere loss in human cells and in mice
Oh et al., J Immunol 2013
(Asthma) :
Pin1 was activated by IL-5, whereas simultaneous
IL-5 and anti-Fas treatment modestly reduced peptidyl isomerase activity but
induced Pin1 to associate with FADD after its phosphorylation at Ser ( 194 )