Gene interactions and pathways from curated databases and text-mining

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MAPK3 — PHKA2

Text-mined interactions from Literome

Rosengart et al., Shock 2002 : Moreover, CD pretreatment abrogated adherence induced activation of Pyk2 , a major focal adhesion kinase, and ERK 1/2, a component of the mitogen activated protein kinase ( MAPK ) signaling pathway, and it completely inhibited LPS induced ERK 1/2 activation
Heidkamp et al., Am J Physiol Cell Physiol 2005 (Heart Failure...) : PYK2 overexpression had no effect on ERK1/2, but increased JNK1/2 and p38 ( MAPK ) phosphorylation from fourfold to eightfold compared with GFP overexpression
Hodges et al., Invest Ophthalmol Vis Sci 2006 : Roles of protein kinase C, Ca2+, Pyk2 , and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK
Anand et al., Mol Immunol 2009 (MAP Kinase Signaling System...) : Inhibition of Pyk2 activity using a pharmacological inhibitor, Tyrphostin A9 significantly attenuated LPS induced Pyk2 tyrosine phosphorylation, p38 MAP kinase ( MAPK ) activation, NF-kappaB activation, and MCP-1 expression