Gene interactions and pathways from curated databases and text-mining

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CREB1 — PENK

Text-mined interactions from Literome

Kobierski et al., J Neurochem 1999 : Cyclic AMP dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src related kinase
Kim et al., Mol Cells 2001 (MAP Kinase Signaling System) : Therefore, we examined possible involvement of the phosphorylated form of JNK, as well as CREB , in the regulation of KA-induced proenkephalin and immediate early genes ( IEGs ) expression in the rat hippocampus
Borsook et al., Mol Endocrinol 1994 : These results suggest a model in which proenkephalin gene expression in the paraventricular nucleus is regulated by CREB in response to hypertonic stress
Bacher et al., J Neurochem 1996 (Second Messenger Systems) : These results suggest that Fos and/or other components of AP-1 transcription factors, rather than CREB or other preexisting proteins, play a specific role in the induction of the proenkephalin gene in bovine chromaffin cells
Monnier et al., DNA Cell Biol 1998 : These results indicate a cooperative effect of AP1 and CREB on PENK transcription