Gene interactions and pathways from curated databases and text-mining

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CASP5 — PDLIM7

Text-mined interactions from Literome

Nitta et al., Cell Signal 2003 (Cell Transformation, Viral) : Moreover, LMP1 induced activation of caspase-3 via the activation of NF-kappaB
Boya et al., Oncogene 2003 : Our data indicate that caspase independent MMP is rate limiting for LMP mediated caspase activation
Huang et al., J Pharmacol Exp Ther 2009 : Taken together, we show that GSK-3beta exhibits a mechanism of ER stress induced lysosomal apoptosis in leukemia involving caspase-2 induced LMP and cathepsin B relocation, which result in caspase-8 and -3 activation
Cho et al., Invest Ophthalmol Vis Sci 2012 : Increases in zinc levels and oxidative stress, excessive activation of autophagy flux, and ultimately the occurrence of LMP and consequent caspase activation may contribute to the well established retinal cytotoxicity of TAM
Huai et al., J Cell Sci 2013 : Both a caspase non-cleavable p75 mutant and the mitochondrially localized antioxidant MitoQ prevent LMP mediated by TNFa plus CHX and partially interfere with apoptosis induction