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IGF2 — PDGFB

Text-mined interactions from Literome

Novosyadlyy et al., Lab Invest 2006 (Fibrosis...) : IGF-I and PDGF-BB differentially affected IGF-IR and PDGFR signaling ... PDGF-BB prevented IGF-I induced downregulation of the IGF-IR , but did not affect expression of its cognate receptor subunits ... In conclusion, the presented data demonstrate that the PDGFR signaling requires a functional IGF-IR and that PDGF-BB stabilizes the IGF-IR function through preventing the IGF-I induced downregulation of the IGF-IR
Rydziel et al., Endocrinology 1996 : In conclusion, normal Ob cells express the PDGF-B gene, and TGF beta 1 induces its transcription, whereas bFGF, IGF-I , and PDGF-BB do not enhance the levels of PDGF-B mRNA
Gangji et al., Endocrinology 1998 : We also determined mechanisms involved in the regulation of IGF-II by platelet derived growth factor (PDGF) BB , fibroblast growth factor-2 (FGF-2), and transforming growth factor (TGF) beta1