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IGF2 — PDE3B

Text-mined interactions from Literome

Ahmad et al., J Immunol 2000 : In F/V cells, IGF-1 increased PKB, PDE3B , and PDE4 activities approximately 2-fold ... In F/B cells, IGF-1 , in a wortmannin-sensitive manner, increased PKB activity approximately 10-fold and PDE3B phosphorylation and activity ( approximately 4-fold ), but increased PDE4 to the same extent as in F/V cells
Ahmad et al., Cell Signal 2000 : Furthermore, IGF-1 dependent stimulation of p42/p44 MAPK and PDE3B was abolished in serum deprived cells and this was associated with apoptosis ... Therefore, IGF-1 dependent regulation of PDE3B may be linked to cell survival through PI3K and not p42/p44 MAPK
Sadler et al., Mol Endocrinol 1991 : This pharmacological evidence demonstrates a necessary role for PDE III in insulin-, IGF-I- , and p21ras induced meiotic cell division in Xenopus laevis oocytes