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PDE3A — PRKAR2A

Text-mined interactions from Literome

Tsukada et al., Neurosci Lett 2002 : To examine whether the PKA activation is due to inhibition of phosphodiesterase III (PDE III) by cyclic GMP, we applied PDE III-specific inhibitors and found that the inhibitions activated PKA
Murthy et al., Am J Physiol Cell Physiol 2002 : PKA dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle
Lim et al., Am J Physiol Gastrointest Liver Physiol 2005 : The PKA inhibitor KT-5720 ( 0.5 microM ) and milrinone ( 3 microM ), a phosphodiesterase (PDE) III inhibitor , blocked the effect of CO on I ( Ba )
Ding et al., Proc Natl Acad Sci U S A 2005 : PDE3A down-regulation activated cAMP/PKA signaling, leading to ICER up-regulation via PKA dependent stabilization of ICER
Murthy et al., Am J Physiol Gastrointest Liver Physiol 2008 : We have previously shown that cAMP levels are regulated by PKA mediated phosphorylation of cAMP-specific phosphodiesterase 3A (PDE3A) and PDE4D5 ; the latter is the only PDE4D isoform expressed in smooth muscle