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AKT1 — PDCD4

Text-mined interactions from Literome

Zeng et al., Am J Physiol Gastrointest Liver Physiol 2006 (Inflammation) : However, when NF-kappaB mediated or phosphatidylinositol 3-kinase/Akt proinflammatory signaling was blocked, flagellin could induce programmed cell death
Palamarchuk et al., Cancer Res 2005 : Because Pdcd4 has two putative Akt phosphorylation sites at Ser ( 67 ) and Ser ( 457 ), we investigated whether Akt phosphorylates and regulates Pdcd4
Li et al., J Biol Chem 2007 (Anoxia...) : Adenoviral expression of constitutively active AKT and lithium chloride mediated inhibition of GSK3beta reduce the potentiated programmed cell death elicited by pleiotrophin
Cheng et al., Transplant Proc 2008 : Recently, it has been shown that Akt phosphorylation activates mammalian target of rapamycin (m-TOR) and inhibits programmed cell death including apoptosis and autophagy
Engel et al., Arch Gynecol Obstet 2011 (Carcinoma...) : Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers
Wang et al., Mol Diagn Ther 2010 (Stomach Neoplasms) : Inhibition of Akt by the phosphoinositide 3-kinase (PI3K) inhibitor LY294002 induced PDCD4 activity and enhanced TRAIL sensitivity in TRAIL-resistant gastric cancer cells
Guo et al., Genes & cancer 2011 : Conversely, ectopic expression of Pdcd4 inhibited AKT phosphorylation and cyclin D1 expression, suggesting that Pdcd4 regulates AKT activity and cyclin D1 expression