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IL12A — PDCD1LG2
Text-mined interactions from Literome
Nguyen et al., J Exp Med 2002
:
In this study, cross linking
B7-DC with the monoclonal antibody sHIgM12 directly potentiates dendritic cell ( DC ) function by enhancing DC presentation of major histocompatibility complex-peptide complexes, promoting DC survival ; and
increasing secretion of
interleukin (IL)-12p70 , a key T helper cell type 1 promoting cytokine
Lewkowich et al., Mucosal Immunol 2013
:
Decreased AHR was associated with enhanced serum interleukin (IL)-12 p40, and in vitro stimulation of DCs with allergen and
PD-L2-Fc reduced
IL-12 p70 production, suggesting that PD-L2 inhibits allergen-driven IL-12 production